Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11050)
Related Products (11050)
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2-Benzylideneheptan-1-ol-d5
0 ImagesCat. No.: HY-W018679SSynonyms: alpha-Amylcinnamyl alcohol-d52-Benzylideneheptan-1-ol-d5 is deuterated labeled 2-Benzylideneheptan-1-ol.
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4-Fluoro-N,N-diisopropylbenzamide-d4
0 ImagesSynonyms: N,N-Diisopropyl-4-fluorobenzamide-d44-Fluoro-N,N-diisopropylbenzamide-d4 (N,N-Diisopropyl-4-fluorobenzamide-d4) is the deuterium labeled 4-Fluoro-N,N-diisopropylbenzamide (HY-W416378).
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1,3-Propanediol-d8
0 Images1,3-Propanediol-d8 is the deuterium labeled 1,3-Propanediol. 1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism.
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Tetrabenazine Impurity-d6
0 ImagesCat. No.: HY-166382SCAS No.: 2244238-16-0Tetrabenazine Impurity-d6 is the deuterium labeled Tetrabenazine Impurity.
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Flavoxate-d4 (hydrochloride)
0 ImagesCat. No.: HY-B0549ASCAS No.: 1189678-43-0Flavoxate-d4 hydrochloride (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate hydrochloride (Rec-7-0040; DW61) is an orally active L-type Ca2+ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions.
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Isopentyl isobutyrate-d7
0 ImagesCat. No.: HY-W087985SCAS No.: 1335401-86-9Synonyms: Isobutyric acid isoamyl Ester-d7Isopentyl isobutyrate-d7 is deuterated labeled Isopentyl isobutyrate.
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L-Dopa-d3
0 ImagesCat. No.: HY-113404S1CAS No.: 157929-66-3
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Cefazolin-13C2,15N sodium
0 ImagesCat. No.: HY-W654098CAS No.: 1346602-30-9Cefazolin-13C2,15N (sodium) is 13C and 15N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
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N-(2-Benzoylmercaptopropionyl)glycine ethyl ester-d3
0 ImagesCat. No.: HY-144410SCAS No.: 1189930-99-1N-(2-Benzoylmercaptopropionyl)glycine ethyl ester-d3 is the deuterium labeled N-(2-Benzoylmercaptopropionyl)glycine ethyl ester.
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Choriogonadotropin, Arg-13C6,15N4, Lys-13C6,15N2
0 ImagesCat. No.: HY-176348SChoriogonadotropin, Arg-13C36, 15N4, Lys-13C6, 15N2 is the 13C- and 15N-labeled Choriogonadotropin.
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Evogliptin-d9
0 ImagesCat. No.: HY-117985SSynonyms: DA-1229-d9Evogliptin-d9 (DA-1229-d9) is deuterium labeled Evogliptin. Evogliptin (DA-1229) is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation.
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9-Phenylcarbazole-d13
0 ImagesCat. No.: HY-33672SCAS No.: 2847910-31-8Synonyms: N-Phenylcarbazole-d139-Phenylcarbazole-d13 (N-Phenylcarbazole-d13) is the deuterium labeled 9-Phenylcarbazole (HY-33672).
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10α-Methoxy-9,10-dihydrolysergol-d3
0 ImagesCat. No.: HY-W654262Synonyms: ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity)-d310α-Methoxy-9,10-dihydrolysergol-d3 is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity).
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Elagolix-d6 sodium
0 ImagesCat. No.: HY-W751574Synonyms: NBI-56418-d6 sodiumElagolix-d6 (sodium) (NBI-56418-d6 (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
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Thiamphenicol-d3-1
0 ImagesSynonyms: Thiophenicol-d3-1; Dextrosulphenidol-d3-1Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479). Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria).
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Maltose monohydrate-13C
0 ImagesCat. No.: HY-N2024AS2Maltose monohydrate-13C is the 13C labeled isotope of Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
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Maresin 2-d5
0 ImagesCat. No.: HY-119684SMaresin 2-d5 is the d5-labeled Maresin 2 (HY-119684). Maresin 2 is an anti-inflammatory and pro-resolving mediator. Maresin 2 drives intestinal epithelial cell migration by activating the focal cell-matrix adhesion signaling pathway in primary human intestinal epithelial cells, thereby promoting mucosal wound repair. Maresin 2 alleviates nociceptive and anxiety-like behaviors in rats with type 1 diabetes by inhibiting IL-1β in the spinal cord and prefrontal cortex. Maresin 2 attenuates allergic airway inflammation in mice by inhibiting the activation of the NLRP3 inflammasome, Th2-type immune responses, and oxidative stress. Maresin 2 inhibits inflammatory and neuropathic trigeminal neuralgia and reduces neuronal activation in the trigeminal ganglion. Maresin 2 promotes inflammation resolution and mucosal repair after DSS-induced colitis or biopsy-induced colonic mucosal injury.
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(R)-Hydroxytolterodine-d14
0 ImagesCat. No.: HY-76569S1CAS No.: 1191280-58-6Synonyms: PNU-200577-d14; 5-Hydroxymethyl Tolterodine-d14(R)-Hydroxytolterodine-d14 is deuterated labeled Desfesoterodine (HY-76569). Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053). Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats.
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1,2,3,4-Tetrahydroquinoxaline-d4
0 ImagesCat. No.: HY-W012652SCAS No.: 1822872-69-4Synonyms: Quinoxaline, 1,2,3,4-tetrahydro-d41,2,3,4-Tetrahydroquinoxaline-d4 (Quinoxaline, 1,2,3,4-tetrahydro-d4) is the deuterium labeled 1,2,3,4-Tetrahydroquinoxaline.
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Desmethylcitalopram-d4 hydrochloride
0 ImagesCat. No.: HY-113739S1Synonyms: DCIT-d4 hydrochlorideDesmethylcitalopram-d4 hydrochloride is deuterated labeled Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM.
